- Sic1 Mutants
- sic1∆
- sic1∆ cdh1∆
- sic1∆ cdh1∆ GALL-CDC20
- sic1∆ cdc6∆2-49
- sic1∆ cdc6∆2-49 cdh1∆
- sic1∆ cdc6∆2-49 cdh1∆ GALL-CDC20
- GAL-CLB2 sic1∆
- GAL-CLB5 sic1∆
- CLB5-db∆ sic1∆
- APC-A sic1∆
- APC-A sic1∆ cdc6∆2-49
- cdc14-ts sic1∆
- cln1∆ cln2∆ sic1∆
- cln3∆ bck2∆ sic1∆
- cln1∆ cln2∆ cln3∆ sic1∆
- swi5∆
- swi5∆ GAL-CLB2
- swi5∆ cdh1∆
- swi5∆ cdh1∆ GAL-SIC1
- GAL-SIC1
- GAL-SIC1-db∆
- GAL-SIC1 cln1∆ cln2∆
- GAL-SIC1 GAL-CLN2 cln1∆ cln2∆
- GAL-SIC1 cln1∆ cln2∆ cdh1∆
- GAL-SIC1 GAL-CLN2 cln1∆ cln2∆ cdh1∆
- CLB2-db∆ multicopy SIC1
- CLB2-db∆ GAL-SIC1
- cdc14-ts GAL-SIC1
- cdc14ts then GAL-SIC1
- APC-A cdh1∆ GAL-SIC1
- APC-A cdh1∆ multi-copy SIC1
GAL-SIC1
debug: ,
test user =
test db =
Simulation:
Change of parameters: ksc1'=0.12, MDT=150.
Length of G1 phase: 144.8 min.
Mass at division: 2.81.
Experiments:
Nugroho, T.T. and Mendenhall, M.D. (1994). An inhibitor of yeast cyclin-dependent protein kinase plays an important role in ensuring the genomic integrity of daughter cells. Mol. Cell. Biol. 14:3320-3328.
[Abstract] [Article]
[Abstract] [Article]
Verma, R., Annan, R.S., Huddleston, M.J., Carr, S.A., Reynard, G. and Deshaies, R.J. (1997a). Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase. Science 278:455-460.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Verma, Fig. 3B, viable. Nugroho, Fig. 2, most cells are viable but large.
Comments: Size 1.1X WT.
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